CHARACTERISTICS OF HANDGRIP STRENTH AND ITS ASSOCIATED FACTORS IN PATIENTS WITH CHRONIC RENAL FAILURE UNDERGOING PERIODIC HEMODIALYSIS AT CAN THO CITY GENERAL HOSPITAL IN 2026
Main Article Content
Abstract
Aims: To describe the prevalence of low handgrip strength and analyze several associated factors among patients with chronic kidney disease undergoing maintenance hemodialysis.
Methods: An analytical cross-sectional study was conducted on 228 patients with chronic kidney disease receiving maintenance hemodialysis at Can Tho City General Hospital from August to December 2025. Handgrip strength was measured using a handgrip dynamometer, and low handgrip strength was defined according to the AWGS 2019 criteria.
Results: The prevalence of low handgrip strength among patients undergoing maintenance hemodialysis was 81.1%. In the multivariable regression model, low handgrip strength was significantly associated with malnutrition (OR=5.42, p=0.002), unemployment (OR=2.52, p=0.033), and increased age (OR=1.04, p=0.006).
Conclusion: Low handgrip strength is common among patients undergoing maintenance hemodialysis. Handgrip strength measurement using a dynamometer is a simple method that should be considered for assessing muscle function in this patient population.
Keywords
handgrip strength, dynamometer, maintenance hemodialysis, muscle weakness
Article Details
References
2. Massini G, Caldiroli L, Molinari P, Carminati FMI, Castellano G, Vettoretti S. Nutritional strategies to prevent muscle loss and sarcopenia in chronic kidney disease: what do we currently know? Nutrients. 2023;15(14):3107. doi:10.3390/nu15143107.
3. Sabatino A, Cuppari L, Stenvinkel P, Lindholm B, Avesani CM. Sarcopenia in chronic kidney disease: what have we learned so far? J Nephrol. 2021;34(4):1347-72. doi:10.1007/s40620-020-00840-y.
4. Chen LK, Woo J, Assantachai P, Auyeung TW, Chou MY, Iijima K, et al. Asian Working Group for Sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment. J Am Med Dir Assoc. 2020;21(3):300-7.e2. doi:10.1016/j.jamda.2019.12.012.
5. Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16-31. doi:10.1093/ageing/afy169.
6. Yoowannakul S, Tangvoraphonkchai K, Vongsanim S, Mohamed A, Davenport A. Differences in the prevalence of sarcopenia in haemodialysis patients: the effects of gender and ethnicity. J Hum Nutr Diet. 2018;31(5):689-96. doi:10.1111/jhn.12555.
7. Hwang SH, Lee DH, Min J, Jeon JY. Handgrip strength as a predictor of all-cause mortality in patients with chronic kidney disease undergoing dialysis: a meta-analysis of prospective cohort studies. J Ren Nutr. 2019;29(6):471-9. doi:10.1053/j.jrn.2019.01.002.
8. Lopes LCC, Gonzalez MC, Avesani CM, Prado CM, Peixoto MdRG, Mota JF. Low hand grip strength is associated with worse functional capacity and higher inflammation in people receiving maintenance hemodialysis. Nutrition. 2022;93:111469. doi:10.1016/j.nut.2021.111469.
9. Li C, Pan X, Xu S, Hu J, Zhong X, Wen L, et al. Handgrip strength is independently associated with physical quality of life in patients undergoing maintenance hemodialysis: a cross-sectional study. Front Nutr. 2024;11:1478209. doi:10.3389/fnut.2024.1478209.
10. Kalantar-Zadeh K, Kleiner M, Dunne E, Lee GH, Luft FC. A modified quantitative subjective global assessment of nutrition for dialysis patients. Nephrol Dial Transplant. 1999;14(7):1732-8. doi:10.1093/ndt/14.7.1732.
11. Lin YL, Liou HH, Wang CH, Lai YH, Kuo CH, Chen SY, et al. Impact of sarcopenia and its diagnostic criteria on hospitalization and mortality in chronic hemodialysis patients: a 3-year longitudinal study. J Formos Med Assoc. 2020;119(7):1219-29. doi:10.1016/j.jfma.2019.10.020.
12. Abdala R, Elena del Valle E, Negri AL, Bridoux P, Paganti LG, Bravo M, et al. Sarcopenia in hemodialysis patients from Buenos Aires, Argentina. Osteoporos Sarcopenia. 2021;7(2):75-80. doi:10.1016/j.afos.2021.04.001.
13. Silva MZC, Antonio KJ, Reis JMS, Alves LS, Caramori JCT, Vogt BP. Age, diabetes mellitus, and dialysis modality are associated with risk of poor muscle strength and physical function in hemodialysis and peritoneal dialysis patients. Kidney Res Clin Pract. 2021;40(2):294-303. doi:10.23876/j.krcp.20.159.
14. Newman AB, Kupelian V, Visser M, Simonsick EM, Goodpaster BH, Kritchevsky SB, et al. Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort. J Gerontol A Biol Sci Med Sci. 2006;61(1):72-7. doi:10.1093/gerona/61.1.72.
15. Yun I, Park YS, Park EC, Jang SI. Association between changes in working status and hand-grip strength among Korean middle-aged and older adults: a longitudinal panel study. Sci Rep. 2022;12(1):12897. doi:10.1038/s41598-022-16373-2.
16. Bakkal H, Dizdar OS, Erdem S, Kulakoğlu S, Akçakaya B, Katırcılar Y, et al. The relationship between hand grip strength and nutritional status determined by Malnutrition Inflammation Score and biochemical parameters in hemodialysis patients. J Ren Nutr. 2020;30(6):548-55. doi:10.1053/j.jrn.2020.01.026.
17. Xavier JS, Góes CRd, Borges MCC, Caramori JCT, Vogt BP. Handgrip strength thresholds are associated with Malnutrition Inflammation Score (MIS) in maintenance hemodialysis patients. J Ren Nutr. 2022;32(6):739-43. doi:10.1053/j.jrn.2022.01.014.
18. Soeters PB, Wolfe RR, Shenkin A. Hypoalbuminemia: pathogenesis and clinical significance. JPEN J Parenter Enteral Nutr. 2019;43(2):181-93. doi:10.1002/jpen.1451.
Similar Articles
- Van Sy NGUYEN, Le Hong Dung LE, OPTIMIZATION AND VALIDATION OF METHOD FOR DETERMINATION OF NATTOKINASE ACTIVITY IN DIETARY SUPPLEMENTS BY ULTRAVIOLET SPECTROPHOTOMETRY , Vietnam Journal of Nutrition & Food: Vol. 21 No. 5 (2025)
You may also start an advanced similarity search for this article.