HOÀN THIỆN CÔNG NGHỆ SẢN XUẤT, ĐÁNH GIÁ HOẠT TÍNH SINH HỌC CỦA SẢN PHẨM NANO ĐÔNG TRÙNG HẠ THẢO TAM ĐẢO

Abstract

Aims: The study objectives were to perfect the production technology of Tam Dao Nano Cordyceps products, with a capacity of 3-5 kg per batchand and to evaluate the biological activity and basic product standards.

Methods: Tam Dao Cordyceps after harvest, were freeze-dried and ground into fine powder with a particle size of 1-2 mm, then extracted in an mixture (a mixture of alcohol/water at v/v ratios of 1/1, 1/2, and 2/1) at 50°C for 2 hours. The extract was collected and filtered. The formula was used for creating the Chitosan-PEG carrier (Chitosan/PEG ratio (v/v): 5/5, 6/4, 7/3, 8/2, 9/1).

The quality of the Tam Dao Nano Cordyceps was determined by indices such as particle size, adenosine content, cordycepin content, and evaluation of certain biological activities.

Results: The technology to produce Tam Dao Nano Cordyceps products with a capacity of 3-5 kg per batch was perfected: Cordyceps powder with a particle size of 1-2 mm was extracted in an alcohol/water mixture at a 1/1 ratio (v/v) at 50°C for 2 hours. The chitosan/PEG carrier system was in a 7/3 (v/v) ratio. The Tam Dao Nano Cordyceps product meets the standard TCCS No. 01:2024/HTX, ensuring compliance with food safety regulations (QCVN 8-3:2012/BYT and QCVN 8-2:2012/BYT).

Conclusion: The production technology for Tam Dao Nano Cordyceps products with a capacity of 3-5 kg per batch was perfected; identify biological activity and basic product standards TCCS No. 01:2024/HTX.