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Issue: Vol. 22 No. 2E (2026)
Section: ORIGINAL RESEARCH
DOI: 10.56283/1859-0381/1091
Date Published: 28/04/2026
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DO VC, DAO TM, NGUYEN DD, PHAM DM. CHANGES IN NUTRITIONAL STATUS AND DIETARY INTAKE AMONG PATIENTS WITH UPPER GASTROINTESTINAL CANCER RECEIVING MULTIMODAL TREATMENT AT MILITARY HOSPITAL 175. Tạp chí Dinh dưỡng và Thực phẩm. 2026;22(2E):65-73. doi:10.56283/1859-0381/1091

CHANGES IN NUTRITIONAL STATUS AND DIETARY INTAKE AMONG PATIENTS WITH UPPER GASTROINTESTINAL CANCER RECEIVING MULTIMODAL TREATMENT AT MILITARY HOSPITAL 175

Viet Canh DO1,2, Tien Manh DAO3, Duy Dong NGUYEN4, Duc Minh PHAM4
1 Military Hospital 13
2 Vietnam Military Medical University
3 Military Hospital 175, Ho Chi Minh City
4 Military Hospital 103, Vietnam Military Medical University

Main Article Content

Abstract

Aims: To describe longitudinal changes in nutritional status and dietary intake among patients with upper gastrointestinal cancer receiving multimodal treatment at Military Hospital 175.


Methods: A longitudinal observational study was conducted in 62 patients with esophageal or gastric cancer. Assessments were performed before treatment (T0), after 2 weeks (T1), after 1 month (T2), and after 3 months (T3). Nutritional status was evaluated using body weight, BMI, and the Patient-Generated Subjective Global Assessment (PG-SGA). Dietary intake was assessed using repeated 24-hour dietary recalls.


Results: The mean age was 62.7 ± 8.5 years; 91.9% were male, and 85.5% had stage III–IV disease. Body weight decreased significantly from 55.45 ± 10.30 kg at T0 to 51.43 ± 8.19 kg at T3, and BMI declined from 21.94 ± 4.07 to 20.34 ± 3.24 kg/m² (p=0.001). PG-SGA score increased from 8.66 ± 3.35 at T0 to 9.69 ± 2.85 at T1, then decreased to 6.43 ± 3.03 at T3 (p<0.001). Energy intake decreased at T1 and then partially recovered by T3, with a significant overall change over time (p=0.011). Protein and carbohydrate intake showed similar early declines followed by partial recovery, whereas lipid intake remained relatively stable.


Conclusion: Patients with upper gastrointestinal cancer experienced significant nutritional changes during the first three months of multimodal treatment. The early treatment phase, particularly the first two weeks, represents a vulnerable period for nutritional deterioration. Regular assessment using PG-SGA, anthropometric indicators, and dietary intake evaluation should be integrated into multimodal cancer care to support timely nutritional intervention.

Keywords

Upper gastrointestinal cancer, PG-SGA, BMI, dietary intake, malnutrition.

Article Details

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