NUTRITIONAL STATUS OF BREAST CANCER PATIENTS UNDERGOING CHEMOTHERAPY AT NATIONAL CANCER HOSPITAL, VIETNAM, 2024–2025
Main Article Content
Abstract
Aims: To assess the nutritional status and associated factors among breast cancer patients undergoing chemotherapy at National Cancer Hospital during 2024–2025.
Methods: A cross-sectional study was conducted on 142 post-surgical breast cancer patients receiving chemotherapy at Internal Medicine Departments 5 and 6 of the Hospital.
Results: The findings show that the prevalence of overweight and obesity based on BMI was 35,2% and 17,6%, respectively; and 2,1% were classified as chronic energy deficiency. Anthropometric assessments revealed that 41,6% of patients had moderate central fat distribution and 4.9% had high central fat accumulation. Additionally, 47,2% of the patients had a high waist-to-hip ratio. Furthermore, 60% of the patients were at risk of sarcopenia based on calf circumference, and 52,8% demonstrated reduced muscle strength as assessed by handgrip strength. Irregular physical activity was associated with an increased risk of sarcopenia (OR = 2,5; 95% CI: 1,2–5,0).
Conclusion: The study demonstrated that breast cancer patients undergoing chemotherapy exhibited high prevalence of overweight, obesity, and sarcopenia risk, indicating the presence of sarcopenic obesity - a condition characterized by concurrent excess adiposity and reduced muscle mass - which may adversely affect treatment response and efficacy.
Keywords
Breast cancer, chemotherapy, nutritional status, overweight, obesity, Vietnam National Cancer Hospital.
Article Details
References
2. International Agency for Research on Cancer. Viet Nam – Global Cancer Observatory: Cancer Today (GLOBOCAN 2022). 2022; Available from: https://gco.iarc.who.int/media/globocan/factsheets/populations/704-viet-nam-fact-sheet.pdf.
3. Playdon MC, Bracken MB, Sanft TB, et al. Weight Gain After Breast Cancer Diagnosis and All-Cause Mortality: Systematic Review and Meta-Analysis. J Natl Cancer Inst. 2015;107(12):djv275. doi:10.1093/jnci/djv275.
4. Hoang Ha Linh, Le Xuan Hung, Pham Quang Thai, et al. Nutritional status of breast cancer patients and the related factors at Vietnam National Cancer hospital in 2019-2020. Journal of Preventive Medicine. 2020;30(4):42-51.
5. Bộ y tế, Quyết định 2892/ QĐ-BYT Hướng dẫn chẩn đoán và điều trị bệnh béo phì 2022, Bộ y tế.
6. Bộ y tế, Quyết định số 2598/QĐ-BYT, Hướng dẫn quy trình kỹ thuật về dinh dưỡng lâm sàng 2025, Bộ Y tế. p. 24.
7. Rose Berlin Piodena-Aportadera M, Lau S, Chew J, et al. Calf Circumference Measurement Protocols for Sarcopenia Screening: Differences in Agreement, Convergent Validity and Diagnostic Performance. Ann Geriatr Med Res. 2022;26(3):215-224. doi: 10.4235/agmr.22.0057..
8. de Souza Mamede VF, Bernabé RAM, Santos TG, da Silva LL, de Souza Vieira M, Marques-Rocha JL, Guandalini VR. Risk of sarcopenia in women with breast cancer: a comparative analysis of screening tools. BMC Cancer. 2025;25(1):839. doi: 10.1186/s12885-025-14062-7.